HIGH-AFFINITY KAINATE AND DOMOATE RECEPTORS IN RAT-BRAIN

被引：128

作者：

LOMELI, H ^{[1
]}

WISDEN, W ^{[1
]}

KOHLER, M ^{[1
]}

KEINANEN, K ^{[1
]}

SOMMER, B ^{[1
]}

SEEBURG, PH ^{[1
]}

机构：

[1] UNIV HEIDELBERG,CTR MOLEC BIOL,MOLEC NEUROENDOCRINOL LAB,INF 282,W-6900 HEIDELBERG,GERMANY

来源：

FEBS LETTERS | 1992年 / 307卷 / 02期

关键词：

GLUTAMATE RECEPTOR; HIGH-AFFINITY KAINATE BINDING; DOMOATE;

D O I：

10.1016/0014-5793(92)80753-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mammalian brain expresses receptors which bind the potent neurotoxins, kainate and domoate, with high affinity, and which form a subclass of ionotropic glutamate receptors. A new member of these receptors, expressed in both adult and embryonic CNS is compared in its ligand binding properties to its closely sequence-related homologs.

引用

页码：139 / 143

页数：5

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