ENDORPHINS AND EXTINCTION - DIFFERENTIAL ACTIONS ON APPETITIVE AND ADVERSIVE TASKS

被引：44

作者：

LEMOAL, M ^{[1
]}

KOOB, GF ^{[1
]}

BLOOM, FE ^{[1
]}

机构：

[1] SALK INST BIOL STUDIES, AV DAVIS CTR BEHAV NEUROBIOL, SAN DIEGO, CA 92112 USA

来源：

LIFE SCIENCES | 1979年 / 24卷 / 18期

关键词：

D O I：

10.1016/0024-3205(79)90245-5

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Alpha and gamma endorphin both inhibited the extinction of a runway task for water reward in water-deprived rats after subcutaneous injections of microgram dosages. At similar doses, these same peptides produced opposing actions on the extinction of a pole-jumping avoidance task: alpha endorphin inhibited and gamma endorphin facilitated extinction. The effects of these peptides on motivated behavior may thus be situation-dependent. © 1979.

引用

页码：1631 / 1636

页数：6

共 13 条

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