SYNTHESIS OF A PERDEUTERATED PHOSPHOLIPID - 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE-D72

被引:121
作者
KINGSLEY, PB [1 ]
FEIGENSON, GW [1 ]
机构
[1] CORNELL UNIV, BIOCHEM MOLEC & CELL BIOL SECT, ITHACA, NY 14853 USA
关键词
D O I
10.1016/0009-3084(79)90083-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The synthesis of a perdeuterated phospholipid - 1,2-dimyristoyl-sn-glycero-3-phosphocholine-d72 (DMPC-d72) - is described. Ordinary (protonated) DMPC was prepared by the same synthetic route and its properties were found to be the same as those of commercial DMPC. The uses of partially deuterated and perdeuterated phospholipids in NMR studies are discussed. © 1979.
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页码:135 / 147
页数:13
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