STUDIES ON FLUORINE CONTAINING HETEROCYCLIC-COMPOUNDS .4. REACTIONS OF 3-NITRO-4-CHLOROBENZOTRIFLUORIDE AND 3,5-DINITRO-4-CHLOROBENZOTRIFLUORIDE WITH 5-MEMBERED HETEROCYCLES

被引:3
作者
CHEN, MJ
CHI, CS
CHEN, QY
机构
[1] Shanghai Institute of Organic Chemistry, Shanghai 200032
来源
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 1990年 / 54卷 / 1-4期
关键词
5-linked compounds; benzotriazole; displacement; Heterocycles; organo-fluorine; thiazole;
D O I
10.1080/10426509008042124
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The reactions of 3-nitro-4-chlorobenzotrifluoride (1a) and 3, 5-dinitro-4-chlorobenzotrifluoride (1b) with heterocycles (2-5) are described. Six S-linked and N-substituted heterocycles (6, 9-11, 13), such as 2-(2-nitro-4-trifluoromethylphenylthio) benzothiazole (9a), were prepared from the reactions of 1a with benzotriazole (2), 2-mercaptobenzothiazole (5a) and 2-mercaptobenzoxazole (5b) and from the reactions of 1b with 2. 1, 2, 4-triazole (3) and 5a in DMF respectively, 1a reacted with 2-mercaptothiazoline (4) to give desired product 7 and bis(2-nitro-4-trifluoromethylphenyl) thioether (8). 3-(2-Benzoxazolyl)-2-benzoazolinethione (15) was obtained from the reaction of 1b with 5b. The spectral data and elemental analyses were fully in accord with the proposed structures, and the possible mechanisms for these compounds and other by-products were discussed. © 1990, Taylor & Francis Group, LLC. All rights reserved.
引用
收藏
页码:87 / 93
页数:7
相关论文
共 14 条
[1]  
BROKKE ME, 1972, Patent No. 3697536
[2]  
CHI C, UNPUB
[3]  
CHI CS, 1971, J ORG CHEM, V36, P242
[4]   2,2'-THIOBIS(BENZOXAZOLE) AND 3-(2-BENZOXAZOLYL)-2-BENZOAZOLINETHIONE [J].
DAMICO, JJ ;
CAMPBELL, RH .
JOURNAL OF ORGANIC CHEMISTRY, 1967, 32 (10) :3196-&
[5]  
DAMICO JJ, 1961, Patent No. 3002977
[6]  
Diehl R., 1980, US Patent, Patent No. 4240822
[7]  
Filler R., 1982, BIOMEDICAL ASPECTS F
[8]  
HUGHES PG, 1975, Patent No. 1379754
[9]  
ISAMU S, 1970, Patent No. 7208162
[10]  
ROUSSEL C, 1979, THIAZOLE ITS DERIV 2, P369