MEASUREMENTS OF EXCISION REPAIR TRACTS FORMED DURING MEIOTIC RECOMBINATION IN SACCHAROMYCES-CEREVISIAE

被引：48

作者：

DETLOFF, P

PETES, TD

机构：

[1] UNIV N CAROLINA,DEPT BIOL,CHAPEL HILL,NC 27599

[2] UNIV CHICAGO,DEPT MOLEC GENET & CELL BIOL,CHICAGO,IL 60637

来源：

MOLECULAR AND CELLULAR BIOLOGY | 1992年 / 12卷 / 04期

关键词：

D O I：

10.1128/MCB.12.4.1805

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

During meiotic recombination in the yeast Saccharomyces cerevisiae, heteroduplexes are formed at a high frequency between HIS4 genes located on homologous chromosomes. Using mutant alleles of the HIS4 gene that result in poorly repaired mismatches in heteroduplex DNA, we find that heteroduplexes often span a distance of 1.8 kb. In addition, we show that about one-third of the repair tracts initiated at well-repaired mismatches extend 900 bp.

引用

页码：1805 / 1814

页数：10

共 43 条

[1] MULTIPLE GLOBAL REGULATORS CONTROL HIS4 TRANSCRIPTION IN YEAST
ARNDT, KT
STYLES, C
FINK, GR
[J]. SCIENCE, 1987, 237 (4817) : 874 - 880
[2] REPAIR OF HETERODUPLEX PLASMID DNA AFTER TRANSFORMATION INTO SACCHAROMYCES-CEREVISIAE
BISHOP, DK
KOLODNER, RD
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1986, 6 (10) : 3401 - 3409
[3] A POSITIVE SELECTION FOR MUTANTS LACKING OROTIDINE-5'-PHOSPHATE DECARBOXYLASE ACTIVITY IN YEAST - 5-FLUORO-OROTIC ACID RESISTANCE
BOEKE, JD
LACROUTE, F
FINK, GR
[J]. MOLECULAR & GENERAL GENETICS, 1984, 197 (02): : 345 - 346
[4] BORTS RH, 1989, GENETICS, V123, P69
[5] REPAIR OF SPECIFIC BASE PAIR MISMATCHES FORMED DURING MEIOTIC RECOMBINATION IN THE YEAST SACCHAROMYCES-CEREVISIAE
DETLOFF, P
SIEBER, J
PETES, TD
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1991, 11 (02) : 737 - 745
[6] DETLOFF PD, UNPUB
[7] DICAPRIO L, 1976, GENETICS, V84, P697
[8] THE NUCLEOTIDE-SEQUENCE OF THE HIS4 REGION OF YEAST
DONAHUE, TF
FARABAUGH, PJ
FINK, GR
[J]. GENE, 1982, 18 (01) : 47 - 59
[9] GENETIC SELECTION FOR MUTATIONS THAT REDUCE OR ABOLISH RIBOSOMAL RECOGNITION OF THE HIS4 TRANSLATIONAL INITIATOR REGION
DONAHUE, TF
CIGAN, AM
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1988, 8 (07) : 2955 - 2963
[10] POSTMEIOTIC SEGREGATION IN SACCHAROMYCES
ESPOSITO, MS
[J]. MOLECULAR AND GENERAL GENETICS, 1971, 111 (03): : 297 - &

← 1 2 3 4 5 →