NITROGEN-SOURCE-INDUCED ACTIVATION OF NEUTRAL TREHALASE IN SCHIZOSACCHAROMYCES-POMBE AND PACHYSOLEN-TANNOPHILUS - ROLE OF CAMP AS 2ND-MESSENGER

被引：6

作者：

SOTO, T ^{[1
]}

FERNANDEZ, J ^{[1
]}

VICENTESOLER, J ^{[1
]}

CANSADO, J ^{[1
]}

GACTO, M ^{[1
]}

机构：

[1] UNIV MURCIA,FAC BIOL,DEPT GENET & MICROBIOL,E-30071 MURCIA,SPAIN

来源：

FEMS MICROBIOLOGY LETTERS | 1995年 / 132卷 / 03期

关键词：

TREHALASE ACTIVATION; CAMP; SIGNAL TRANSDUCTION; SCHIZOSACCHAROMYCES POMBE; PACHYSOLEN TANNOPHILUS;

D O I：

10.1111/j.1574-6968.1995.tb07838.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Resting cells of the fission yeast Schizosaccharomyces pombe, suspended in buffer with glucose. responded to the addition of asparagine by increasing trehalase activity. This response was preceded by a peak in cAMP concentration. The addition of the nitrogen source to resting cells, devoid of the catalytic subunit of cAMP-dependent protein kinase, produced the transient increase in cAMP but did not promote any change in trehalase activity. In the budding yeast Pachysolen tannophilus, the activation of trehalase by nitrogen source was also accompanied by a sharp peak in cAMP. These results suggest that in the two yeasts cAMP acts as a second messenger in the transduction of the nitrogen-source-induced signal causing the activation of trehalase.

引用

页码：229 / 232

页数：4

共 11 条

[1]

CARRILLO D, 1992, FEMS MICROBIOL LETT, V98, P61

[2] CYCLIC-AMP SIGNALING PATHWAY AND TREHALASE ACTIVATION IN THE FISSION YEAST SCHIZOSACCHAROMYCES-POMBE [J].

CARRILLO, D ;

VICENTESOLER, J ;

GACTO, M .

MICROBIOLOGY-SGM, 1994, 140 :1467-1472

[3] ACTIVATION OF CYTOPLASMIC TREHALASE BY CYCLIC-AMP-DEPENDENT AND CYCLIC-AMP-INDEPENDENT SIGNALING PATHWAYS IN THE YEAST CANDIDA-UTILIS [J].

CARRILLO, D ;

VICENTESOLER, J ;

FERNANDEZ, J ;

SOTO, T ;

CANSADO, J ;

GACTO, M .

MICROBIOLOGY-UK, 1995, 141 :679-686

[4] ACTIVATION OF TREHALASE DURING GROWTH INDUCTION BY NITROGEN-SOURCES IN THE YEAST SACCHAROMYCES-CEREVISIAE DEPENDS ON THE FREE CATALYTIC SUBUNITS OF CAMP-DEPENDENT PROTEIN-KINASE, BUT NOT ON FUNCTIONAL RAS PROTEINS [J].

DURNEZ, P ;

PERNAMBUCO, MB ;

ORIS, E ;

ARGUELLES, JC ;

MERGELSBERG, H ;

THEVELEIN, JM .

YEAST, 1994, 10 (08) :1049-1064

[5] NUTRIENT-INDUCED ACTIVATION OF TREHALASE IN NUTRIENT-STARVED CELLS OF THE YEAST SACCHAROMYCES-CEREVISIAE - CAMP IS NOT INVOLVED AS 2ND MESSENGER [J].

HIRIMBUREGAMA, K ;

DURNEZ, P ;

KELEMAN, J ;

ORIS, E ;

VERGAUWEN, R ;

MERGELSBERG, H ;

THEVELEIN, JM .

JOURNAL OF GENERAL MICROBIOLOGY, 1992, 138 :2035-2043

[6] GLUCOSE-INDUCED HYPERACCUMULATION OF CYCLIC-AMP AND DEFECTIVE GLUCOSE REPRESSION IN YEAST STRAINS WITH REDUCED ACTIVITY OF CYCLIC AMP-DEPENDENT PROTEIN-KINASE [J].

MBONYI, K ;

VANAELST, L ;

ARGUELLES, JC ;

JANS, AWH ;

THEVELEIN, JM .

MOLECULAR AND CELLULAR BIOLOGY, 1990, 10 (09) :4518-4523

[7]

MUEDA T, 1994, J BIOL CHEM, V269, P9632

[8] RIGOROUS FEEDBACK-CONTROL OF CAMP LEVELS IN SACCHAROMYCES-CEREVISIAE [J].

NIKAWA, J ;

CAMERON, S ;

TODA, T ;

FERGUSON, KM ;

WIGLER, M .

GENES & DEVELOPMENT, 1987, 1 (09) :931-937

[9] FERMENTABLE SUGARS AND INTRACELLULAR ACIDIFICATION AS SPECIFIC ACTIVATORS OF THE RAS ADENYLATE-CYCLASE SIGNALING PATHWAY IN YEAST - THE RELATIONSHIP TO NUTRIENT-INDUCED CELL-CYCLE CONTROL [J].

THEVELEIN, JM .

MOLECULAR MICROBIOLOGY, 1991, 5 (06) :1301-1307

[10]

THEVELEIN JM, 1985, J GEN MICROBIOL, V131, P3199

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