EFFECT OF NUMBER OF PRIMED CELLS ON PRODUCTION OF IGM AND IGG ANTIBODIES IN AN ADOPTIVE SECONDARY RESPONSE

被引：14

作者：

KONTIAIN.S

MAKELA, O

机构：

[1] Department of Serology and Bacteriology, University of Helsinki, Helsinki, 25

[2] State Serum Institute, Helsinki, 28

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY | 1968年 / 34卷 / 05期

关键词：

D O I：

10.1159/000230136

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Aliquots from a hapten-primed spleen cell population were transferred to irradiated syngcneic hosts. Immune inactivation of hapten-coupled bacteriophage was used to assay antibody. IgM and IgG antibodies were determined by the combined reduction-hapten- inhibition method [5]. Excellent memory was found in the production of IgM antibodies by primed cells. Proportionally more IgM anti-hapten was produced when the density of primed cells was low than when the density was high. © 1968 S. Karger AG, Basel.

引用

页码：417 / &

共 21 条

[1]

BROWNSTONE A, 1966, IMMUNOLOGY, V10, P465

[2] QUANTITATIVE STUDIES OF ADOPTIVE IMMUNOLOGICAL MEMORY IN MICE .2. LINEAR TRANSMISSION OF CELLULAR MEMORY [J].