STUDY OF GENERAL DISTRIBUTION OF 46 CHROMOSOMES IN HUMAN METAPHASE PLATES

This study, based on the square distances of chromosome centromeres from the center of a cell, shows after circular transformation, that the general dispersion of the 46 chromosomes is uniform, except on the periphery of the cell. It is found that the chromosomes taken separately have not a random distribution, but have peculiar positions. In males, chromosomes 1, 13-14-15 and 21-22 tend to lie nearer the middle of the nucleus, while chromosomes, Y, 6-X and 4-5 tend to lie nearer the periphery. In female mitoses the chromosome 13-14-15, 21-22 and 19-20 and 19-20 have a more central position, while chromosomes 4-5, 3, 2 and 16 tend to lie nearer the periphery. © 1968 Springer-Verlag.