PARATHYROID HORMONE PRODUCTION IN VITRO BY HUMAN PARATHYROID CELLS TRANSFORMED BY SIMIAN VIRUS 40

被引:30
作者
DEFTOS, LJ
RABSON, AS
BUCKLE, RM
AURBACH, GD
POTTS, JT
机构
[1] National Institutes of Health, Bethesda
[2] Southampton General Hospital, Southampton
关键词
D O I
10.1126/science.159.3813.435
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Cells from a human parathyroid adenoma were infected with simian virus 40 and maintained through 13 subcultures in monolayer tissue culture. For more than 9 months, these transformed" cells continued to produce parathyroid hormone which was identified by radioimmunoassay and density-gradient ultracentrifugation."
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页码:435 / &
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