KINETICS OF TERNARY COMPLEX-FORMATION BETWEEN DIHYDROFOLATE-REDUCTASE, COENZYME, AND INHIBITORS

被引：60

作者：

DUNN, SMJ ^{[1
]}

KING, RW ^{[1
]}

机构：

[1] NATL INST MED RES,DIV MOLEC PHARMACOL,LONDON NW7 1AA,ENGLAND

来源：

BIOCHEMISTRY | 1980年 / 19卷 / 04期

关键词：

D O I：

10.1021/bi00545a024

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：766 / 773

页数：8

共 22 条

[1]

Blakley R. L., 1969, FRONT BIOL

[2]

BLAKLEY RL, 1971, ANN NY ACAD SCI, V186, P119

[3]

Caldin E., 1964, FAST REACTIONS SOLUT

[4] C-13 NUCLEAR MAGNETIC-RESONANCE STUDY OF INTERACTION OF LIGANDS WITH ARGININE RESIDUES IN DIHYDROFOLATE-REDUCTASE [J].

COCCO, L ;

BLAKLEY, RL ;

WALKER, TE ;

LONDON, RE ;

MATWIYOFF, NA .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1977, 76 (01) :183-188

[5]

CZERLINSKI GG, 1966, CHEM RELAXATION

[6] LARGE-SCALE PURIFICATION AND CHARACTERIZATION OF DIHYDROFOLATE-REDUCTASE FROM A METHOTREXATE-RESISTANT STRAIN OF LACTOBACILLUS-CASEI [J].

DANN, JG ;

OSTLER, G ;

BJUR, RA ;

KING, RW ;

SCUDDER, P ;

TURNER, PC ;

ROBERTS, GCK ;

BURGEN, ASV ;

HARDING, NGL .

BIOCHEMICAL JOURNAL, 1976, 157 (03) :559-571

[7] KINETICS OF LIGAND-BINDING TO DIHYDROFOLATE-REDUCTASE - BINARY COMPLEX-FORMATION WITH NADPH AND COENZYME ANALOGS [J].

DUNN, SMJ ;

BATCHELOR, JG ;

KING, RW .

BIOCHEMISTRY, 1978, 17 (12) :2356-2364

[8] P-31 NMR-STUDIES OF NADPH AND NADP+ BINDING TO L-CASEI DIHYDROFOLATE-REDUCTASE [J].

FEENEY, J ;

BIRDSALL, B ;

ROBERTS, GCK ;

BURGEN, ASV .

NATURE, 1975, 257 (5527) :564-566

[9] CIRCULAR-DICHROISM STUDIES OF DIHYDROFOLATE-REDUCTASE FROM A METHOTREXATE-RESISTANT STRAIN OF ESCHERICHIA-COLI-B, MB 1428 - TERNARY COMPLEXES [J].

GREENFIELD, NJ .

BIOCHIMICA ET BIOPHYSICA ACTA, 1975, 403 (01) :32-46

[10]

HILLCOAT BL, 1967, J BIOL CHEM, V242, P4777

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