NMR AND CONFORMATIONAL-ANALYSIS OF THE CAPSULAR POLYSACCHARIDE FROM STREPTOCOCCUS-PNEUMONIAE TYPE-4

被引：36

作者：

JONES, C

CURRIE, F

FORSTER, MJ

机构：

[1] Laboratory of Molecular Structure, National Institute for Biological Standards and Control, South Mimms,, Herts. Herts. EN6 3QG, Blanche Lane

来源：

CARBOHYDRATE RESEARCH | 1991年 / 221卷

关键词：

D O I：

10.1016/0008-6215(91)80051-N

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The H-1- and C-13-n.m.r. data on the capsular polysaccharide (1) produced by Streptococcus pneumoniae type 4, the depyruvated polysaccharide (2), and a tetrasaccharide (3a) derived by Smith degradation of 2 were used as constraints on a computer-generated model of the conformation of 1 and to assess the effects of the pyruvic acetal substituent on the conformation. The dynamics of the polysaccharide systems and the influence of the pyruvic acetal were investigated using C-13-n.m.r. relaxation measurements.

引用

页码：95 / 121

页数：27

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