Pedigree Study of Familial Alzheimer Disease

被引：25

作者：

Powell, Diane ^{[1
]}

Folstein, Marshal F. ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Psychiat, Baltimore, MD 21205 USA

来源：

JOURNAL OF NEUROGENETICS | 1984年 / 1卷 / 02期

关键词：

Alzheimer disease; pedigree study;

D O I：

10.3109/01677068409107085

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Twenty-one families with familial Alzheimer disease were ascertained in a dementia clinic and assessed by multiple family interviews. Eight autopsies were reviewed. The age of onset varied from 25 to 85. Seven pedigrees showed evidence of 3 generation transmission. Paternal age of the founders of 4 lines which could be assessed was higher than controls.

引用

页码：189 / 197

页数：9

共 41 条

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