THROMBOTIC THROMBOCYTOPENIC PURPURA AND MYOGLOBINURIC ACUTE-RENAL-FAILURE FOLLOWING RADIATION-THERAPY IN A PATIENT WITH POLYMYOSITIS AND CERVICAL-CANCER

被引:10
作者
MAKINO, H
NAGAKE, Y
MORIWAKI, K
HIRAKAWA, S
KATAYAMA, T
YANAI, H
TAKAHASHI, K
AKAGI, T
OTA, Z
机构
[1] The Third Department of Internal Medicine, Okayama University Medical School, Okayama
[2] Department of Gynecology and Obstetrics, Okayama University Medical School, Okayama
[3] The Second Department of Pathology, Okayama University Medical School, Okayama
关键词
RHABDOMYOLYSIS; MYOGLOBINURIA; ACUTE TUBULAR NECROSIS; MICROANGIOPATHIC HEMOLYTIC ANEMIA;
D O I
10.2169/internalmedicine.34.24
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 73-year-old woman was admitted to receive radiation treatment for uterine cervical cancer, however a complex series of events ensued, leading to death. She developed an acute exacerbation of polymyositis complicated by thrombotic thrombocytopenic purpura, rhabdomyolysis and acute renal failure. Radiation therapy may have produced an immune disturbance leading to the acute exacerbation of polymyositis. Auto-immune-mediated endothelial damage might have triggered a series of events leading to thrombotic thrombocytopenic purpura. Rhabdomyolysis seemed to be the main cause of acute renal failure.
引用
收藏
页码:24 / 27
页数:4
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