UNDER-MODIFIED Y-BASE IN A TRANSFER-RNA-PHE ISOACCEPTOR OBSERVED IN TUMOR-CELLS

被引：29

作者：

KUCHINO, Y ^{[1
]}

KASAI, H ^{[1
]}

YAMAIZUMI, Z ^{[1
]}

NISHIMURA, S ^{[1
]}

BOREK, E ^{[1
]}

机构：

[1] AMC CANC RES CTR,LAKEWOOD,CO 80214

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 565卷 / 01期

关键词：

Modified Y base; tRNA; Tumor-specific RNA;

D O I：

10.1016/0005-2787(79)90098-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A fluorescent wye (Ye) was isolated from tRNAPhe specific to Ehrlich ascites cells. The structure was determined to be α-amino-β-hydroxy-4,9-dihydro-4,6-dimethyl-9-oxo-1H-imidazo(1,2-a)purine-7-butyric acid: namely the compound lacking methyl carboxyl and methyl groups and thus is an under-modified precursor of hydroxy-Y base present in normal liver tRNAPhe. © 1979.

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页码：215 / 218

页数：4

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