NEW BIOACTIVE HEPTENES FROM MELODORUM-FRUTICOSUM (ANNONACEAE)

被引：57

作者：

JUNG, JH

PUMMANGURA, S

CHAICHANTIPYUTH, C

PATARAPANICH, C

FANWICK, PE

CHANG, CJ

MCLAUGHLIN, JL

机构：

[1] PURDUE UNIV,SCH PHARM & PHARMACAL SCI,DEPT CHEM,W LAFAYETTE,IN 47907

[2] CHULALONGHKORN UNIV,FAC PHARMACEUT SCI,DEPT PHARMACEUT CHEM,BANGKOK 10500,THAILAND

来源：

TETRAHEDRON | 1990年 / 46卷 / 15期

关键词：

D O I：

10.1016/S0040-4020(01)87811-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

By guiding fractionation with brine shrimp lethality, three novel compounds, with cytotoxic activities against human tumor cell lines, have been isolated from the bark of Melodorum fruticosum Lour.(Annonaccae). These compounds have benzoyl moieties in common with a c7 dienone or lactone terminal which appears to arise from a heptose or the equivalents. They were named melodienone, isomelodienone, and acetylmelodorinol. © 1990.

引用

页码：5043 / 5054

页数：12

共 22 条

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