THE RESOLUTION OF RACEMIC 1,2-DIOLS BY THE ESTERASE CATALYZED-HYDROLYSIS OF THE CORRESPONDING CYCLIC CARBONATE

被引：20

作者：

BARTON, P

PAGE, MI

机构：

[1] Department of Chemical Sciences, The University of Huddersfield, Huddersfield, HD1 3DH England, Queensgate

来源：

TETRAHEDRON | 1992年 / 48卷 / 36期

关键词：

DIOL RESOLUTION; PIG LIVER ESTERASE;

D O I：

10.1016/S0040-4020(01)90383-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Racemic 1-phenyl-1,2-ethane diol can be resolved by the pig liver esterase catalysed hydrolysis of the corresponding cyclic carbonate to give the (R) and (S) 1-phenyl-1,2-ethane diol with an ee of 97 and 78% respectively.

引用

页码：7731 / 7734

页数：4

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