IN-VIVO VERSUS IN-VITRO ASSAYS FOR ASSESSMENT OF T-CELL AND B-CELL FUNCTION

被引：30

作者：

BACHMANN, MF ^{[1
]}

KUNDIG, TM ^{[1
]}

机构：

[1] PRINCESS MARGARET HOSP, ONTARIO CANC INST, DEPT MED BIOPHYS, TORONTO M4X 1K9, ONTARIO, CANADA

来源：

CURRENT OPINION IN IMMUNOLOGY | 1994年 / 6卷 / 02期

关键词：

D O I：

10.1016/0952-7915(94)90108-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

As mice deficient in a particular gene provide an increasing number of novel in vivo models, in vivo assays that examine immune function are becoming a central issue. We found that the sensitivities of in vivo and in vitro assays are strikingly different. These differences have important implications for the interpretation and biological relevance of results.

引用

页码：320 / 326

页数：7

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