PROTOSTRYCHNINE, A NEW ALKALOID FROM STRYCHNOS-NUX-VOMICA

被引:15
作者
BASER, KHC
BISSET, NG
HYLANDS, PJ
机构
[1] Pharmacognosy Research Laboratories, Department of Pharmacy, Chelsea College, London, SW3 6LX, Manresa Road
关键词
biosynthesis; indole alkaloids; Loganiaceae; prestrychnine; protostrychnine; Strychnos nux-vomica;
D O I
10.1016/S0031-9422(00)81909-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The tertiary bases from a sample of Strychnos nux-vomica contain, as well as the expected strychnine and brucine, an unusually high proportion of 4-hydroxy and 4-hydroxy-3-methoxy compounds. The biosynthetic implications of the isolation of a new alkaloid, 12β,13α-dihydro-12α-hydroxyisostrychnine, named protostrychnine, are discussed. © 1979.
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页码:512 / 514
页数:3
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