ANTIULCEROGENIC AND ANTIINFLAMMATORY STUDIES WITH SHILAJIT

被引:50
作者
GOEL, RK [1 ]
BANERJEE, RS [1 ]
ACHARYA, SB [1 ]
机构
[1] BANARAS HINDU UNIV,INST MED SCI,DEPT PHARMACOL,VARANASI 221005,UTTAR PRADESH,INDIA
关键词
D O I
10.1016/0378-8741(90)90102-Y
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
In folk medicine, shilajit has been used to treat diverse clinical conditions ranging from peptic ulcer to bone healing. The present study was conducted to evaluate the possible antiulcerogenic and antiinflammatory activities of shilajit obtained from the rocky mountains of Zarlek, Badekshan, Afghanistan. Shilajit increased the carbohydrate/protein ratio and decreased gastric ulcer index, indicating an increased mucus barrier. Shilajit was found to have significant antiinflammatory effect in carrageenan-induced acute pedal oedema, granuloma pouch and adjuvant-induced arthritis in rats. The results of the present study thus substantiate the use of shilajit in peptic ulcer and inflammation. © 1990.
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页码:95 / 103
页数:9
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