DELAYED-HYPERSENSITIVITY TO 6-METHYL-PREDNISOLONE IN HENOCH-SCHONLEIN SYNDROME

被引：6

作者：

ASTONE, A

ROMANO, A

PIETRANTONIO, F

GARCOVICH, A

VENUTI, A

BARONE, C

机构：

[1] UNIV CATTOLICA SACRO CUORE, IST CLIN MED, LARGO A GEMELLI 8, I-00168 ROME, ITALY

[2] UNIV CATTOLICA SACRO CUORE, IST CLIN DERMATOL, I-00168 ROME, ITALY

来源：

ALLERGY | 1992年 / 47卷 / 04期

关键词：

HENOCH-SCHONLEIN SYNDROME; HYPERSENSITIVITY REACTION; 6-METHYL-PREDNISOLONE; SKIN TESTS;

D O I：

10.1111/j.1398-9995.1992.tb02085.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

We report a case of allergic reaction to oral 6-methyl-prednisolone in a patient with Henoch Schoenlein syndrome. When this syndrome was first diagnosed the patient was started on 6-methyl-prednisolone orally and after 4 days he developed a pruriginous generalized maculo-papular eruption. The rash disappeared 1 week after withdrawal of 6-methyl-prednisolone. The skin tests performed 1 month after with main food allergens were negative. Patch test with 0. 10 ml of solution containing 6-methyl-prednisolone 40 mg/ml was positive after 48 and 72 h. The cutaneous biopsy on the patch tested skin revealed a perivascular infiltrate of lymphocytes, histiocytes and eosinophils.

引用

页码：436 / 438

页数：3

共 8 条

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