THE CELLULAR BASIS OF FANCONI SYNDROME

被引:10
作者
BAUM, M
机构
[1] Texas University SW Medical Center, Dallas, TX
来源
HOSPITAL PRACTICE | 1993年 / 28卷 / 11期
关键词
D O I
10.1080/21548331.1993.11442879
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In this syndrome, all solutes are prevented from crossing the apical membrane of the proximal renal tubule cell; hence, investigations have focused on generalized transport dysfunction, namely intracellular ATP activity. Experiments suggest that intracellular adenine nucleotide degradation secondary to phosphate depletion causes a decline in ATP.
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页码:137 / &
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