MOLECULAR-CONFORMATION OF ERABUTOXIN-B - ATOMIC COORDINATES AT 2.5 A RESOLUTION

被引:95
作者
KIMBALL, MR [1 ]
SATO, A [1 ]
RICHARDSON, JS [1 ]
ROSEN, LS [1 ]
LOW, BW [1 ]
机构
[1] COLUMBIA UNIV,DEPT BIOCHEM,NEW YORK,NY 10032
基金
美国国家卫生研究院;
关键词
D O I
10.1016/0006-291X(79)91500-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Atomic coordinates determined from a 2.5 Å electron density map are given for erabutoxin b, a sea snake venom postsynaptic neurotoxin. The principal structural features, anti-parallel β pleated sheet, β bulge and β bends are described. The erabutoxin b structure is discussed as structural prototype of this class of homologous curare-mimetic neurotoxins from both land and sea snakes. © 1979.
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页码:950 / 959
页数:10
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