RELATIONSHIP BETWEEN CONCENTRATIONS OF PROSTAGLANDIN-A1, E1, E2 AND E2-ALPHA AND RATES OF CELL-PROLIFERATION

被引：38

作者：

KARMALI, RA

HORROBIN, DF

MENEZES, J

PATEL, P

机构：

[1] CLIN RES INST MONTREAL,MONTREAL H2W 1R7,QUEBEC,CANADA

[2] UNIV MONTREAL,PEDIAT RES CTR,MONTREAL 101,QUEBEC,CANADA

[3] UNIV MONTREAL,DEPT MICROBIOL,MONTREAL 101,QUEBEC,CANADA

来源：

PHARMACOLOGICAL RESEARCH COMMUNICATIONS | 1979年 / 11卷 / 01期

关键词：

D O I：

10.1016/S0031-6989(79)80100-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In vitro effects on cell proliferation of a Raji lymphoid cell line of several prostaglandins, both in the physiological and pharmacological concentration range have been studied. Inhibition of PG synthesis by indomethacin inhibited the cell proliferation. Chloroquine was also inhibitory and PGE2 prevented this suppressive action in an apparently competitive manner. © 1979 The Italian Pharmacological Society.

引用

页码：69 / 75

页数：7

共 25 条

[1] CULTURED HUMAN-SKIN FIBROBLASTS AND ARTERIAL CELLS PRODUCE A LABILE PLATELET-INHIBITORY PROSTAGLANDIN [J].