KINETICS OF REACTIONS IN HETEROCYCLES .6. REPLACEMENT OF 2-ALKYLTHIO 2-ALKYLSULPHINYL AND 2-ALKYLSULPHONYL GROUPS FROM QUINOXALINES BY METHOXIDE ION

被引：15

作者：

BARLIN, GB

BROWN, WV

机构：

[1] Department of Medical Chemistry, John Curtin School of Medical Research, Australian National University, Canberra, ACT

来源：

JOURNAL OF THE CHEMICAL SOCIETY B-PHYSICAL ORGANIC | 1969年 / 04期

关键词：

D O I：

10.1039/j29690000333

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Kinetic studies of the reactions of 2-alkylsulphonyl-, 2-alkylsulphinyl-, and 2-alkylthio-quinoxalines with sodium methoxide showed that for the methyl, ethyl, isopropyl, and t-butyl compounds a decreased reactivity was observed with increasing size of the group. This effect was least for the sulphides (1.8 fold difference) and greatest (140 fold) for sulphoxides. U.v. and 1H n.m.r. spectra are recorded and discussed.

引用

页码：333 / &

共 15 条

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