METABOLISM OF A NEW POSITIVE INOTROPIC AGENT, 3,4-DIHYDRO-6-[4-(3,4-DIMETHOXYBENZOYL)-1-PIPERAZINYL]-2(1H)-QUINOLINONE (OPC-8212) IN THE RAT, MOUSE, DOG, MONKEY AND HUMAN

被引：11

作者：

MIYAMOTO, G

SASABE, H

TOMINAGA, N

UEGAKI, N

TOMINAGA, M

SHIMIZU, T

机构：

来源：

XENOBIOTICA | 1988年 / 18卷 / 10期

关键词：

D O I：

10.3109/00498258809042237

中图分类号：

R9 [药学];

学科分类号：

1007 [药学];

摘要：

引用

页码：1143 / 1155

页数：13

共 13 条

[1]

TISSUE METABOLITES OF TRIFLUOPERAZINE, FLUPHENAZINE, PROCHLORPERAZINE, AND PERPHENAZINE IN RAT - IDENTIFICATION AND SYNTHESIS [J].

BREYER, U ;

PROX, A ;

BERTELE, R ;

GAERTNER, HJ .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1974, 63 (12) :1842-1848

[2]

CONNEY AH, 1960, J PHARMACOL EXP THER, V128, P333

[3]

EINAR S, 1976, XENOBIOTICA, V6, P137

[4]

GAERTNER HJ, 1973, J PHARMACOL EXP THER, V185, P195

[5]

HARBERKANN J, 1950, HOPPESEYLERS Z PHYSL, V285, P97

[6]

METABOLITES OF PIPEMIDIC ACID IN HUMAN-URINE [J].

KUROBE, N ;

NAKAMURA, S ;

SHIMIZU, M .

XENOBIOTICA, 1980, 10 (01) :37-46

[7]

MAGATSU Y, 1981, CHEMOTHERAPY, V29, P119

[8]

HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC PROCEDURE FOR THE DETERMINATION OF A NEW POSITIVE INOTROPIC AGENT, 3,4-DIHYDRO-6-[4-(3,4-(DIMETHOXYBENZOYL)-1-PIPERAZINYL]-2(1H)-QUINOLINONE, IN HUMAN-PLASMA AND URINE [J].

MIYAMOTO, G ;

SASABE, H ;

ODOMI, M ;

SHIMIZU, T .

JOURNAL OF CHROMATOGRAPHY, 1985, 338 (02) :450-455

[9]

MIYAMOTO G, 1984, DRUG RES, V34, P394

[10]

SUZUKI T, 1983, DRUG METAB DISPOS, V11, P377

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