HEREDITARY ANGIO-EDEMA - TREATMENT WITH DANAZOL - REPORT OF A CASE

被引：25

作者：

TAPPEINER, G ^{[1
]}

HINTNER, H ^{[1
]}

GLATZL, J ^{[1
]}

WOLFF, K ^{[1
]}

机构：

[1] UNIV INNSBRUCK,DEPT PEDIAT,A-6020 INNSBRUCK,AUSTRIA

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1979年 / 100卷 / 02期

关键词：

D O I：

10.1111/j.1365-2133.1979.tb05562.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

An 8‐year‐old boy with hereditary angio‐oedema was treated with danazol under close endocrinological supervision. The boy's C1 esterase inhibitor (Clinh) and C4 levels increased rapidly to near normal values under a daily doses of 400 mg and were maintained at about 50% of the normal by maintenance doses of 200 mg danazol every other day. Throughout the entire treatment period (11 months) the boy has been maintained free from attacks of angio‐oedema. No hormonal imbalance was detected in the follow‐up period. Our results indicate that danazol should be suitable for the treatment of HAE not only in adults but also in prepubescent children. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：207 / 212

页数：6

共 21 条

[1]

BLACKMORE WP, 1977, J INT MED RES, V5, P38

[2]

BLOHME G, 1972, ACTA MED SCAND, V192, P293

[3] COMPETITIVE RADIOLIGAND ASSAY FOR DANAZOL (17ALPHA-PREGN-4-EN-20-YNO[2,3-D]ISOXAZOL-17-OL) USING PREGNANT GUINEA-PIG PLASMA [J].