SYMPTOMATIC EPSTEIN-BARR-VIRUS INFECTION AND MULTIPLE-SCLEROSIS

被引：68

作者：

MARTYN, CN ^{[1
]}

CRUDDAS, M ^{[1
]}

COMPSTON, DAS ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,ADDENBROOKES HOSP,SCH CLIN,DEPT NEUROL,CAMBRIDGE CB2 2QQ,ENGLAND

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1993年 / 56卷 / 02期

关键词：

D O I：

10.1136/jnnp.56.2.167

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In a case-control study of 214 patients with multiple sclerosis, recall of infectious mononucleosis in subjects seropositive for Epstein-Barr viral capsid antigen was associated with a relative risk of 2-9 (95% CI 1.1 to 7.2). Those who reported having infectious mononucleosis before the age of 18 years had a relative risk of multiple sclerosis of 7.9 (95% CI 1.7 to 37.9). The pathogenesis of multiple sclerosis may involve an age-dependent host response to Epstein-Barr virus infection.

引用

页码：167 / 168

页数：2

共 7 条

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