A STUDY OF HEAT INACTIVATION OF SERUM ALKALINE PHOSPHATASE BY AN AUTOMATED TECHNIQUE

被引：9

作者：

SMALL, CW

机构：

[1] Pathology Department, Greenlane Hospital, Auckland

来源：

CLINICA CHIMICA ACTA | 1969年 / 23卷 / 02期

关键词：

D O I：

10.1016/0009-8981(69)90051-5

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

A method is described for differentiating alkaline phosphatase of osseous and hepatic origin, employing an automated determination of the rate of inactivation of alkaline phosphatase at 56°. The method was applied to thirty-nine cases in which the liver was the only organ involved, and to sixteen cases of uncomplicated bone disease. A sharp separation between the two groups is shown. Further sera from patients with tissue damage were analysed. Most of these cases were shown, by other evidence, to have predominantly bone or liver damage, and these findings correlated well with the heat inactivation ratios reported. The values obtained in eighty-six normal subjects are also discussed. © 1968.

引用

页码：347 / &

共 13 条

[1] .5. USE OF ANTIBODIES IN DISCRIMINATION OF MULTIPLE MOLECULAR FORMS OF ENZYMES - HUMAN ORGAN ALKALINE PHOSPHATASES - DISCRIMINATION BY SEVERAL MEANS INCLUDING STARCH GEL ELECTROPHORESIS OF ANTIENZYME-ENZYME SUPERNATANT FLUIDS [J].