STEROID-DEPENDENT NEPHROTIC SYNDROME FOLLOWING RENAL-TRANSPLANTATION FOR CONGENITAL NEPHROTIC SYNDROME

被引：13

作者：

LANE, PH

SCHNAPER, HW

VERNIER, RL

BUNCHMAN, TE

机构：

[1] Division of Pediatric Nephrology at University of Minnesota Hospitals, Minneapolis, 55455, Minnesota

[2] Division of Pediatric Nephrology at Children's Hospital, Washington University, St. Louis, Missouri

[3] Cardinal Glennon Children's Hospital, St. Louis University, St. Louis University, Missouri

来源：

PEDIATRIC NEPHROLOGY | 1991年 / 5卷 / 03期

关键词：

CONGENITAL NEPHROTIC SYNDROME; NEPHROTIC SYNDROME; RENAL TRANSPLANT; SOLUBLE IMMUNE RESPONSE SUPPRESSOR;

D O I：

10.1007/BF00867484

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A boy developed recurrent steroid-responsive nephrotic syndrome following renal transplantation for congenital nephrotic syndrome. The first episode was associated with mild tubulointerstitial rejection on kidney biopsy. Subsequent episodes showed normal histology by light microscopy and epithelial foot process fusion on electron microscopy, consistent with minimal change nephrotic syndrome. Serum analysis for soluble immune response suppressor was negative pre-nephrectomy, positive during each bout of nephrotic syndrome, and negative during each remission. This case represents de novo occurrence of steroid-sensitive minimal change nephrotic syndrome following renal transplantation for congenital nephrotic syndrome. We stress the need for histological examination of the renal allograft to diagnose rejection, recurrent disease, or de novo disease.

引用

页码：300 / 303

页数：4

共 22 条

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