ANACINE, A NEW BENZODIAZEPINE METABOLITE OF PENICILLIUM-AURANTIOGRISEUM PRODUCED WITH OTHER ALKALOIDS IN SUBMERGED FERMENTATION

被引：29

作者：

BOYESKORKIS, JM

GURNEY, KA

PENN, J

MANTLE, PG

BILTON, JN

SHEPPARD, RN

机构：

[1] UNIV LONDON IMPERIAL COLL SCI TECHNOL & MED,DEPT BIOCHEM,LONDON SW7 2AZ,ENGLAND

[2] UNIV LONDON IMPERIAL COLL SCI TECHNOL & MED,DEPT CHEM,LONDON SW7 2AZ,ENGLAND

来源：

JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 10期

关键词：

D O I：

10.1021/np50100a008

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A novel benzodiazepine metabolite of an isolate of Penicillium aurantiogriseum from Yugoslavia has been characterized from spectral and biosynthetic evidence. The compound, anacine [1), has been produced on the 60-liter fermenter scale after extensive sporulation induced by batched Ca++, and its biosynthesis was preceded by that of the diketopiperazine fructigenine A [7], for which additional spectral and biosynthetic data have been obtained.

引用

页码：1707 / 1717

页数：11

共 20 条

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