CHANGES IN THE SUBSTRATE SPECIFICITIES OF AN ENZYME DURING DIRECTED EVOLUTION OF NEW FUNCTIONS

被引：69

作者：

HALL, BG

机构：

来源：

关键词：

D O I：

10.1021/bi00517a015

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：4042 / 4049

页数：8

共 15 条

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[3] CORNISHBOWDEN A, 1976, PRINCIPLES ENZYME KI, pCH10
[4] NUMBER OF MUTATIONS REQUIRED TO EVOLVE A NEW LACTASE FUNCTION IN ESCHERICHIA-COLI
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[J]. JOURNAL OF BACTERIOLOGY, 1977, 129 (01) : 540 - 543
[5] HALL BG, 1977, GENETICS, V85, P193
[6] HALL BG, 1975, GENETICS, V81, P427
[7] HALL BG, 1974, GENETICS, V76, P391
[8] EVOLUTION OF A NEW ENZYMATIC FUNCTION BY RECOMBINATION WITHIN A GENE
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (06): : 3529 - 3533
[9] HALL BG, 1978, GENETICS, V89, P453
[10] EXPERIMENTAL EVOLUTION OF A NEW ENZYMATIC FUNCTION - KINETIC-ANALYSIS OF ANCESTRAL (EBG) AND EVOLVED (EBG+) ENZYMES
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[J]. JOURNAL OF MOLECULAR BIOLOGY, 1976, 107 (01) : 71 - 84