INTRAMOLECULAR ADDITION OF VINYL AND ARYL RADICALS TO OXIME ETHERS IN THE SYNTHESIS OF 5-MEMBERED, 6-MEMBERED AND 7-MEMBERED RING-SYSTEMS

被引：73

作者：

BOOTH, SE

JENKINS, PR

SWAIN, CJ

SWEENEY, JB

机构：

[1] UNIV LEICESTER,DEPT CHEM,LEICESTER LE1 7RH,LEICS,ENGLAND

[2] MERCK SHARP & DOHME LTD,HARLOW CM20 2QR,ESSEX,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1994年 / 23期

关键词：

D O I：

10.1039/p19940003499

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The oxime ethers 2a-e have been cyclised with Bu(3)SnH to the alkoxyamino-3-methylidene-chromanes 3a-e. Seven-membered ring formation was observed when the oxime ethers 7a, b were converted into the dibenzo [b,e] oxepines 8a, b under similar conditions. 1-Methoxyaminoindanes 12a, b were produced from the cyclisation of the substrates 11a, b and the cis-fused cyclic products 15a, b and 18 were obtained from compounds 14a, b and 17, respectively.

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页码：3499 / 3508

页数：10

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