FERMENTATION ANALYSIS BY CLUSTERING

被引：7

作者：

GUTHKE, R

ROSSMANN, R

机构：

[1] INST MICROBIOL & EXPTL THERAPY,O-6900 JENA,GERMANY

[2] JENAPHARM GMBH,O-6900 JENA,GERMANY

来源：

BIOPROCESS ENGINEERING | 1991年 / 6卷 / 04期

关键词：

D O I：

10.1007/BF00369253

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

To supervise, stabilize and optimize antibiotic fermentations in the industrial scale expert systems are presently worked out. For the knowledge acquisition various classifiers are tested using a set of 27 nourseothricin fermentation runs. Two methods are applied: optimal clustering by help of minimum variance criterion and hierarchical clustering by help of dendrograms. The fermentations are classified with respect to the specific material costs as well as the product formation kinetics.

引用

页码：157 / 161

页数：5

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