DENITROZATION OF N-NITROSOMORPHOLINE BY LIVER-MICROSOMES - POSSIBLE ROLE OF CYTOCHROME-P-450

被引：64

作者：

APPEL, KE ^{[1
]}

SCHRENK, D ^{[1
]}

SCHWARZ, M ^{[1
]}

MAHR, B ^{[1
]}

KUNZ, W ^{[1
]}

机构：

[1] GERMAN CANC RES CTR,INST BIOCHEM,DEPT MOLEK TOXIKOL,NEUENHEIMER FELD 280,D-6900 HEIDELBERG 1,FED REP GER

来源：

CANCER LETTERS | 1980年 / 9卷 / 01期

关键词：

D O I：

10.1016/0304-3835(80)90135-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：13 / 20

页数：8

共 24 条

[1]

APPEL K, 1976, N-S ARCH PHARMACOL, V293, pR65

[2] BINDING OF NITROSAMINES TO CYTOCHROME-P-450 OF LIVER-MICROSOMES [J].

APPEL, KE ;

RUF, HH ;

MAHR, B ;

SCHWARZ, M ;

RICKART, R ;

KUNZ, W .

CHEMICO-BIOLOGICAL INTERACTIONS, 1979, 28 (01) :17-33

[3]

APPEL KE, 1978, N-S ARCH PHARMACOL, V302, pR20

[4] INFLUENCES OF INDUCERS AND INHIBITORS OF THE MICROSOMAL MONO-OXYGENASE SYSTEM ON THE ALKYLATING INTENSITY OF DIMETHYLNITROSAMINE IN MICE [J].

APPEL, KE ;

SCHWARZ, M ;

RICKART, R ;

KUNZ, W .

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 1979, 94 (01) :47-61

[5]

APPEL KE, 1979, ARCH TOXICOL S, V2, P471

[6] REPRESSION OF DIMETHYLNITROSAMINE-DEMETHYLASE BY TYPICAL INDUCERS OF MICROSOMAL MIXED-FUNCTION OXIDASES [J].

ARCOS, JC ;

BRYANT, GM ;

VENKATESAN, N ;

ARGUS, MF .

BIOCHEMICAL PHARMACOLOGY, 1975, 24 (16) :1544-1547

[7] REPRESSIBLE AND INDUCIBLE ENZYMIC FORMS OF DIMETHYLNITROSAMINE-DEMETHYLASE [J].

ARCOS, JC ;

DAVIES, DL ;

BROWN, CEL ;

ARGUS, MF .

ZEITSCHRIFT FUR KREBSFORSCHUNG UND KLINISCHE ONKOLOGIE, 1977, 89 (02) :181-199

[8]

CZYGAN P, 1974, CANCER RES, V34, P119

[9] EFFECT OF AMINOACETONITRILE ON METABOLISM OF DIMETHYLNITROSAMINE AND METHYLATION OF RNA DURING LIVER CARCINOGENESIS [J].

HADJIOLOV, D ;

MUNDT, D .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1974, 52 (03) :753-756

[10]

HILL DL, 1975, CANCER RES, V35, P296

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