ADAPTIVE-CHANGES IN TOTAL PYRUVATE-DEHYDROGENASE ACTIVITY IN LIPOGENIC TISSUES OF RATS FED HIGH-SUCROSE OR HIGH-FAT DIETS

被引：12

作者：

DASILVA, LA ^{[1
]}

DEMARCUCCI, OL ^{[1
]}

CARMONA, A ^{[1
]}

机构：

[1] UNIV CENT VENEZUELA,FAC MED,IPOSTEL,INST MED EXPTL,APARTADO 54031,CARACAS 1015A,VENEZUELA

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-PHYSIOLOGY | 1992年 / 103卷 / 02期

关键词：

D O I：

10.1016/0300-9629(92)90602-M

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. Pyruvate dehydrogenase complex (PDC) activity was measured in several tissues of rats fed for 7 or 15 days on control, or high-sucrose or high-fat diets. 2. Total activity in adipose tissue increased in the three groups 3-4-fold as compared with chow-fed animals in the first week. Total activity was 60% lower in rats fed the diet containing 22% corn oil for 2 weeks. 3. Hepatic total and PDCa activities were 50-80% higher in rats fed the sucrose diet for 7 or 15 days and decreased 30-40% in those fed on the high-fat diet for 2 weeks.

引用

页码：407 / 411

页数：5

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