PH DEPENDENCE OF NMR SPECTRUM OF MERCAPTOSUCCINIC ACID

被引：10

作者：

LEYDEN, DE

WALTERS, DB

机构：

[1] Department of Chemistry, University of Georgia, Athens

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR SPECTROSCOPY | 1969年 / A 25卷 / 12期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0584-8539(69)80217-5

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

The nuclear magnetic resonance spectrum of aqueous solutions of mercaptosuccinic acid have been studied over a wide pH range. The chemical shifts of the non-labile C-H protons follow the usual titration curve. However, the two vicinal coupling constants display a maximum in one case and a simultaneous minimum in the other case. This observation is interpreted as a result of changes in the rotamer populations caused by electrostatic and steric effects. The relative populations of the three classical rotamers were calculated at various values of pH and were found to be in qualitative agreement with malic acid at a pH where the comparison is valid. © 1969.

引用

页码：1869 / &

共 13 条

[1] THE PROTON RESONANCE SPECTRA AND CONFORMATIONS OF THE PROLINES .2. THE CONFORMATIONS OF TRANS-HYDROXY-L-PROLINE AND CIS-(ALLO) HYDROXY-L-PROLINE IN SOLUTION [J].

ABRAHAM, RJ ;

MCLAUCHLAN, KA .

MOLECULAR PHYSICS, 1962, 5 (05) :513-523

[2] PROTON MAGNETIC RESONANCE SPECTRA OF MALIC ACID AND ITS SALTS IN DEUTERIUM OXIDE [J].

ALBERTY, RA ;

BENDER, P .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1959, 81 (03) :542-546

[3] THE CONFIGURATION OF DEUTERIO-L-MALIC ACID PRODUCED ENZYMATICALLY - SYNTHESIS OF THREO-3-DEUTERIO-DL-MALIC ACID [J].

ANET, FAL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1960, 82 (04) :994-995

[4] AN INVESTIGATION OF INTRAMOLECULAR HYDROGEN BONDING IN SOME MALONIC ACIDS USING NMR TECHNIQUES [J].

EVANS, HB ;

GOLDSTEIN, JH .

SPECTROCHIMICA ACTA PART A-MOLECULAR SPECTROSCOPY, 1968, A 24 (01) :73-+

[5] CONTACT ELECTRON-SPIN COUPLING OF NUCLEAR MAGNETIC MOMENTS [J].

KARPLUS, M .

JOURNAL OF CHEMICAL PHYSICS, 1959, 30 (01) :11-15

[6] STUDY OF SOME MONO- DI- AND TRICARBOXYLIC ACIDS IN AQUEOUS SOLUTION BY NUCLEAR MAGNETIC RESONANCE TECHNIQUE [J].

LOEWENSTEIN, A ;

GILBOA, H .

SPECTROCHIMICA ACTA, 1966, 22 (11) :1939-+

[7] ANALYSIS OF PROTON MAGNETIC RESONANCE SPECTRA OF CYSTEINE AND HISTIDINE AND DERIVATIVES - CONFORMATIONAL EQUILIBRIA [J].

MARTIN, RB ;

MATHUR, R .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1965, 87 (05) :1065-&

[8] NUCLEAR MAGNETIC RESONANCE STUDY OF SOME ALPHA-AMINO ACIDS .1. COUPLING CONSTANTS IN ALKALINE AND ACIDIC MEDIUM [J].

PACHLER, KGR .

SPECTROCHIMICA ACTA, 1963, 19 (12) :2085-2092

[9] NUCLEAR MAGNETIC RESONANCE STUDY OF SOME ALPHA-AMINO ACIDS .2. ROTATIONAL ISOMERISM [J].

PACHLER, KGR .

SPECTROCHIMICA ACTA, 1964, 20 (04) :581-587

[10]

PACHLER KGR, 1967, Z ANAL CHEM FRESENIU, V224, P211

← 1 2 →