GENE FOR PARATHYROID HORMONE-LIKE PEPTIDE IS ON MOUSE CHROMOSOME-6

被引：13

作者：

HENDY, GN

SAKAGUCHI, AY

LALLEY, PA

MARTINEZ, L

YASUDA, T

BANVILLE, D

GOLTZMAN, D

机构：

[1] MCGILL UNIV,DEPT MED,CALCIUM RES LAB,MONTREAL H3A 2T5,QUEBEC,CANADA

[2] UNIV TEXAS,HLTH SCI CTR,DEPT CELLULAR & STRUCT BIOL,SAN ANTONIO,TX 78284

[3] NATL RES COUNCIL CANADA,BIOTECHNOL RES INST,MOLEC GENET LAB,MONTREAL,QUEBEC,CANADA

[4] WAYNE STATE UNIV,DEPT MOLEC BIOL,DETROIT,MI 48202

[5] MCGILL UNIV,DEPT PHYSIOL,MONTREAL H3A 2T5,QUEBEC,CANADA

来源：

CYTOGENETICS AND CELL GENETICS | 1990年 / 53卷 / 2-3期

关键词：

D O I：

10.1159/000132899

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The single-copy parathyroid hormone-like peplide gene (Ptlilh) was assigned to mouse chromosome 6 using a rat PTHLH cDNA as hybridization probe in Southern blot analysis of DN As isolated from a panel of mouse x Chinese hamster cell hybrids. The mouse parathyroid hormone gene (Prh) has previously been assigned to mouse chromosome 7 and the PTHLH and PTH genes have also been shown to be on different chromosomes in human and rat. Therefore, despite significant amino-terminal sequence homology between the PTHLH and PTH peptides. as well as similarities in the structural organization of the human PTH LH and PTH genes, the genes encoding these peptides have discrete chromosomal locations in the mouse, rat, and man. © 1990 S. Karger AG, Basel.

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页码：80 / 82

页数：3

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