CHARACTERIZATION OF THE ANTIBODY-RESPONSE IN CORYNEBACTERIUM-JEIKEIUM SEPTICEMIAS

被引：7

作者：

CLARK, I ^{[1
]}

BURNIE, JP ^{[1
]}

COKE, AP ^{[1
]}

MATTHEWS, RC ^{[1
]}

OPPENHEIM, BA ^{[1
]}

机构：

[1] UNIV MANCHESTER,SCH MED,DEPT MOLEC MICROBIOL,OXFORD RD,MANCHESTER M13 9PT,LANCS,ENGLAND

来源：

EPIDEMIOLOGY AND INFECTION | 1990年 / 105卷 / 02期

基金：

英国惠康基金;

关键词：

D O I：

10.1017/S095026880004783X

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Corynebacterium jeikeium causes septicaemia in neutropenic patients usually after colonizing intravenous lines. This paper reports the results of immunoblotting sera from 14 patients with a C. jeikeium septicaemia. Recovery from the septicaemia was associated with production of both IgM and IgG against antigenic bands of 50, 52 and 110 kDa. Antibody against the 110 kDa band was present in controls but the antibody against the 50 and 52 kDa was specific to those patients who had on-going or previous C. jeikeium infection. A case of C. jeikeium endocarditis is also presented and here recovery was associated with seroconversion to the 50 and 52 kDa bands. © 1990, Cambridge University Press. All rights reserved.

引用

页码：229 / 236

页数：8

共 12 条

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