REQUIREMENTS OF RIBONUCLEIC ACID SYNTHESIS FOR FORMATION OF SALIVARY GLAND SPECIFIC PROTEINS IN LARVAL CHIRONOMUS TENTANS

被引：20

作者：

DOYLE, D

LAUFER, H

机构：

[1] Biological Science Group, The Institute of Cellular Biology, University of Connecticut, Storrs

来源：

EXPERIMENTAL CELL RESEARCH | 1969年 / 57卷 / 2-3期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0014-4827(69)90142-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Chromosomal ribonucleic acid synthesis in salivary gland cells of fourth instar Chironomus tentans larvae can be inhibited for 12-24 h with actinomycin D with no apparent effect on either the synthesis or the secretion of characteristic salivary gland proteins. Uptake, transport across the gland, and secretion of serum albumin are also relatively insensitive to inhibition by actinomycin D, but these processes are also unaffected when salivary gland protein synthesis is blocked with puromycin. The proteins characteristic of the differentiated state of the larval salivary gland appear to be synthesized on relatively stable ribonucleic acid templates, but new ribonucleic acid synthesis is required for further development. © 1969.

引用

页码：205 / &

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