NALOXONE REDUCES FLUID CONSUMPTION IN WATER-DEPRIVED AND NON-DEPRIVED RATS

被引：72

作者：

STAPLETON, JM

OSTROWSKI, NL

MERRIMAN, VJ

LIND, MD

REID, LD

机构：

[1] Rensselaer Polytechnic Institute, Troy, New York

来源：

BULLETIN OF THE PSYCHONOMIC SOCIETY | 1979年 / 13卷 / 04期

关键词：

D O I：

10.3758/BF03335069

中图分类号：

B841 [心理学研究方法];

学科分类号：

040201 ;

摘要：

Naloxone hydrochloride, in doses of.5 to 10 mg/kg intraperitoneally, reduced water consumption by rats fluid deprived for 24 h. Administered intracerebroventricularly, 100 micrograms of naloxone produced similar effects while doses of 50 micrograms or less had no effect. Naloxone (10 mg/kg) also reduced consumption of a palatable solution (10% sucrose, weight/volume) by nondeprived rats. Morphine sulfate (.5 to 2 mg/kg) failed to increase consumption. © 1979, The Psychonomic Society, Inc.. All rights reserved.

引用

页码：237 / 239

页数：3

共 11 条

[1] ENKEPHALIN MAY MEDIATE EUPHORIA AND DRIVE-REDUCTION REWARD [J].

BELLUZZI, JD ;

STEIN, L .

NATURE, 1977, 266 (5602) :556-558

[2]

GITLIN M, 1978, AM J PSYCHIAT, V135, P377

[3]

GOLDSTEIN A, 1978, PSYCHOPHARMACOLOGY G

[4]

HOLTZMAN SG, 1974, J PHARMACOL EXP THER, V189, P51

[5]

JAFFE JH, 1975, PHARMACOLOGICAL BASI

[6] ANTAGONISM OF MORPHINE-INDUCED AVERSIVE-CONDITIONING BY NALOXONE [J].

LEBLANC, AE ;

CAPPELL, H .

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1975, 3 (02) :185-188

[7]

MAICKEL RP, 1977, NEUROPHARMACOLOGY, V16, P861

[8]

RHINES RK, 1977, ACTA NEUROL SCAND, V56, P445

[9]

STAPLETON JM, PHYSL PSYCHOLOGY

[10] STEREOSPECIFIC AVERSIVE PROPERTY OF NARCOTIC-ANTAGONISTS IN MORPHINE-FREE RATS [J].

STOLERMAN, IP ;

PILCHER, CWT ;

DMELLO, GD .

LIFE SCIENCES, 1978, 22 (19) :1755-1762

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