PROPERTIES OF 2 CHROMATOGRAPHICALLY DISTINCT REAGINS IN SERA OF REGWEED ATOPIC INDIVIDUALS

被引:10
作者
GOODFRIEND, L
PERELMUTTER, L
机构
[1] Division of Immunochemistry and Allergy, McGill University Clinic, Royal Victoria Hospital, Montreal, QC
来源
INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY | 1968年 / 33卷 / 01期
关键词
D O I
10.1159/000229976
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
DEAE-Scphadex chromatography was efficacious in separating a minor and major reaginic fraction from each of 6 ragweed-allergic sera. Both reagins had similar skin fixing activity and were equally susceptible to inactivation by heating at 56° C and reduction with 2-mercaptoethanol. The bulk of the reagins in the 2 fractions had the same sedimentation coefficient (7.4 S). The relationship of the 2 reagins to the known immunoglobulin classes was discussed. © 1968 S. Karger AG, Basel.
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页码:89 / +
页数:1
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