TOTAL SYNTHESIS OF NATURAL ALPHA-TOCOPHEROL .3. SYNTHESIS OF SIDE-CHAIN WITH (-)-(S)-2-METHYL-GAMMA-BUTYROLACTONE AS CENTRAL COMPONENT

被引：32

作者：

ZELL, R

机构：

[1] Zentrale Forschungseinheiten der, F. Hoffmann-La Roche & Co. AG, Basel

来源：

HELVETICA CHIMICA ACTA | 1979年 / 62卷 / 02期

关键词：

D O I：

10.1002/hlca.19790620212

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Total Synthesis of Natural α‐Tocopherol (−)‐(S)‐2‐Methyl‐γ‐butyrolactone (2) represents a versatile chiral C5‐synthon. It serves as key intermediate in one of the syntheses of certain isoprenoid derivatives such as (R)‐dihydrocitronellol, (3R, 7R)‐hexahydrofarnesol and vitamin E of natural configurations. Their syntheses are described in detail. Copyright © 1979 Verlag GmbH & Co. KGaA, Weinheim

引用

页码：474 / 480

页数：7

共 10 条

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