DERIVATIVES OF THE PRODUCT OF BAKER YEAST REDUCTION OF ETHYL ACETOACETATE AS PRECURSORS OF FREE-RADICAL CHIRONS OF THE 2(S)-HYDROXYPROPYL MOIETY

被引：6

作者：

HAMDANI, M ^{[1
]}

DEJESO, B ^{[1
]}

DELEUZE, H ^{[1
]}

MAILLARD, B ^{[1
]}

机构：

[1] UNIV BORDEAUX 1,CNRS,CHIM ORGAN & ORGANOMET LAB,URA 35,351 COURS LIBERAT,F-33405 TALENCE,FRANCE

来源：

TETRAHEDRON-ASYMMETRY | 1991年 / 2卷 / 09期

关键词：

D O I：

10.1016/S0957-4166(00)82196-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Baker's yeast reduction of ethyl acetoacetate provided in good yield ethyl 2(S)-hydroxybutanoate. The hydrolysis of the ester function after protection of the hydroxyl yielded an acid which, under BARTON's free radical decarboxylation conditions, produced a free radical chiron of 2(S)-hydroxypropyl moiety; according to the reaction medium various chiral products from reaction of this entity were produced.

引用

页码：867 / 870

页数：4

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