SYNTHESES OF NEW 2.3.4.5-TETRAHYDRO-1H-1-3-BENZODIAZEPINONES

被引：4

作者：

HROMATKA, O

KNOLLMUL.M

DESCHLER, H

机构：

[1] Institut für Organische Chemie der Technischen Hochschule Wien, Wien, A-1060

来源：

MONATSHEFTE FUR CHEMIE | 1969年 / 100卷 / 02期

关键词：

D O I：

10.1007/BF00904090

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Heating (2-aminophenyl)acetamides with formaldehyde in ethanol or diethylene glycol dimethylether yields 2.3.4.5-tetrahydro-1 H-1,3-benzodiazepine-4-ones; 2.3.4.5-tetrahydro-1 H-1.3-benzodiazepine-2-ones are formed by reaction of phosgene with β-(2-aminophenyl)ethylamines. The (2-nitrophenyl)acetamides needed as intermediate compounds were synthesized from the corresponding nitrobenzoic acids by Arndt-Eistert reaction. © 1969 Springer-Verlag.

引用

页码：469 / &

共 14 条

[1]

BAMBERGER E, 1886, BER DTSCH CHEM GES, V19, P2635

[2] INVESTIGATIONS IN HETEROCYCLES .10. SYNTHESIS OF TETRAHYDRO-1,3-BENZODIAZEPINES, A NEW HETEROCYCLIC SYSTEM [J].

DESTEVENS, G ;

DUGHI, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1961, 83 (14) :3087-&

[3]

DESTEVENS G, 1964, Patent No. 3157642

[4]

DESTEVENS G, 1967, Patent No. 3310582

[5]

GABRIEL S, 1883, BER DEUT CHEM GES, V16, P2066

[6]

HUBNER H, 1969, ANN CHEM, V149, P132

[7]

KONIG A, 1899, BER, V32, P782

[8]

MONTAGNE P, 1900, REC TRAV CHIM PAYS B, V19, P55

[9] The stereo isomeric forms of o-Nitrobenzyl-methyl-ketoximes. [J].

Neber, PW ;

Hartung, K ;

Ruopp, W .

BERICHTE DER DEUTSCHEN CHEMISCHEN GESELLSCHAFT, 1925, 58 :1234-1246

[10]

PSCHORR R, 1910, BER, V43, P2547

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