PARAQUAT AND THE EXACERBATION OF OXYGEN-TOXICITY

被引：44

作者：

FRIDOVICH, I

HASSAN, HM

机构：

[1] Irwin Fridovich and H. Moustafa Hassan are, the Department of Biochemistry, Duke University Medical Center, Durham

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1979年 / 4卷 / 05期

关键词：

D O I：

10.1016/0968-0004(79)90395-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Paraquat subverts electron flow from the normal cytochrome pathway and increases intracellular production of superoxide radical. This radical, which is the cause of paraquat toxicity, elicits increased synthesis of the defensive enzyme, superoxide dismutase. © 1979.

引用

页码：113 / 115

页数：3

共 14 条

[1]

AUTOR AP, 1977, BIOCH MECHANISMS PAR

[2] RATES OF RADICAL FORMATION FROM DIPYRIDYLIUM HERBICIDES PARAQUAT, DIQUAT, AND MORFAMQUAT IN HOMOGENATES OF RAT LUNG, KIDNEY, AND LIVER - INHIBITORY EFFECT OF CARBON-MONOXIDE [J].