ESTIMATION OF PARASITIC INFECTION DYNAMICS WHEN DETECTABILITY IS IMPERFECT

被引：37

作者：

NAGELKERKE, NJD

CHUNGE, RN

KINOTI, SN

机构：

[1] Medical Research Centre, Kenya Medical Research Institute, Nairobi

[2] Statistical Institute, Voorburg, 2270 AZ

来源：

STATISTICS IN MEDICINE | 1990年 / 9卷 / 10期

关键词：

D O I：

10.1002/sim.4780091010

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The simultaneous estimation of infection rate, cure rate and detectability of parasitic infections is considered. A new method for this estimation based on a simple statistical model assuming constant transition rates between parasite states is proposed. Repeated observations on the infection status of the same individuals is required for this method. A maximum likelihood approach is used for parameter estimation and the calculation of standard errors of the estimates. The method is illustrated by a longitudinal study of the presence of Giardia lamblia infection in Kenyan children. Copyright © 1990 John Wiley & Sons, Ltd.

引用

页码：1211 / 1219

页数：9

共 16 条

[1]

Bekessy A., Molineaux L., Storey J., Estimation of incidence and recovery rates of Plasmodium falciparum parasitaema from longitudinal data, Bulletin of the World Health Organization, 54, pp. 685-693, (1980)

[2]

Gazin P., Robert V., Cot M., Carnevale P., Plasmodium falciparum incidence and potency in a high seasonal transmission area of Burkina Faso, Transactions of the Royal Society of Tropical Medicine and Hygiene, 82, pp. 50-55, (1988)

[3]

Aron J.L., Malaria epidemiology and detectability, Transactions of the Royal Society of Tropical Medicine and Hygiene, 76, pp. 505-601, (1982)

[4]

Singer B., Cohen J.L., Estimating malaria incidence and recovery rates from panel surveys, Mathematical Biosciences, 49, pp. 273-305, (1980)

[5]

Erratum Mathematical Biosciences, 62, (1982)

[6]

Nedelman J., The prevalence of malaria in Garki, Nigeria: double sampling with a fallible expert, Biometrics, 44, pp. 635-655, (1988)

[7]

Molineaux L., Gramiccia G., The Garki Project: Research on the Epidemiology and Control of Malaria in the Sudan Savanna of West Africa, (1980)

[8]

Chunge R.N., (1989)

[9]

Bartlett M.S., An Introduction to Stochastic Processes, (1966)

[10]

Cox D.R., Hinkley D.V., Theoretical Statistics, (1974)

← 1 2 →