DESIGN AND SYNTHESIS OF A POLYPEPTIDE CONTAINING 1-PYRENYLALANINES AS FLUORESCENT-PROBE FOR 4 ALPHA-HELIX BUNDLE STRUCTURE

被引:30
作者
NISHINO, N
MIHARA, H
TANAKA, Y
FUJIMOTO, T
机构
[1] Department of Applied Chemistry, Faculty of Engineering, Kyushu Institute of Technology, Kitakyushu, 804, Tobata
关键词
PEPTIDE DESIGN AND SYNTHESIS; 4 ALPHA-HELIX BUNDLE; 53-PEPTIDE; BETA-TURN; 1-PYRENYLALANINE;
D O I
10.1016/0040-4039(92)89027-A
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A four alpha-helix bundle polypeptide containing 1-pyrenylalanines was designed and synthesized. The pyrenyl groups effectively behaved as the fluorescent probe for the detection of the bundle structure.
引用
收藏
页码:5767 / 5770
页数:4
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