INDOMETHACIN IN SEVERE TWIN-TO-TWIN TRANSFUSION SYNDROME

被引：15

作者：

JONES, JM

SBARRA, AJ

DILILLO, L

CETRULO, CL

DALTON, ME

机构：

[1] Departments of Maternal Fetal Medicine, Medical Research and Laboratories, St. Margaret's Hospital for Women, Department of Obstetrics and Gynecology, Tufts University School of Medicine, Boston, Massachusetts

来源：

AMERICAN JOURNAL OF PERINATOLOGY | 1993年 / 10卷 / 01期

关键词：

D O I：

10.1055/s-2007-994694

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Despite advances in maternal fetal medicine, the management of severe twin-to-twin transfusion syndrome in the second trimester presents a significant challenge. Presently, there is no uniformly accepted management protocol that is available for the treatment of this syndrome. We report the use of indomethacin in three cases of severe twin-to-twin transfusion syndrome in the second trimester. In the three cases of severe twin-to-twin transfusion syndrome no reduction of amniotic fluid in either sac was demonstrated. Two cases were complicated by single intrauterine fetal death within 72 hours of initiating indomethacin therapy. Because of our experience with these three cases, we conclude that indomethacin does not prevent perinatal mortality in patients with severe twin-to-twin transfusion syndrome.

引用

页码：24 / 26

页数：3

共 18 条

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