CALANONE, A NOVEL COUMARIN, FROM CALOPHYLLUM-TEYSMANNII

被引：39

作者：

GUSTAFSON, KR ^{[1
]}

BOKESCH, HR ^{[1
]}

FULLER, RW ^{[1
]}

CARDELLINA, JH ^{[1
]}

KADUSHIN, MR ^{[1
]}

SOEJARTO, DD ^{[1
]}

BOYD, MR ^{[1
]}

机构：

[1] NCI,DIV CANC TREATMENT,DEV THERAPEUT PROGRAM,FREDERICK,MD 21702

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 32期

关键词：

D O I：

10.1016/S0040-4039(00)78193-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

During a survey of latex samples of Calophyllum teysmannii for anti-HIV coumarins (calanolide A, costatolide), calanone (5), an unprecedented benzoyl substituted coumarin, was isolated and its structure determined by spectroscopic analyses. The known soulattrolide (3), and the related ketone 4 were also isolated. Soulanrolide inhibited the cytopathic effect of in vitro HIV-1 infection, while calanone (5) and the ketone 4 were inactive.

引用

页码：5821 / 5824

页数：4

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