ALTERATION OF PLASMA KETAMINE LEVELS IN MICE BY PROBENECID

被引:3
作者
DAVISSON, JN
机构
[1] College of Pharmacy and Health Sciences, Northeast Louisiana University, Monroe, 71209, Louisiana
来源
EXPERIENTIA | 1979年 / 35卷 / 08期
关键词
D O I
10.1007/BF01949953
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Probenecid increases plasma ketamine levels in mice concurrently with an enhancement of duration of loss of righting reflex. The magnitude of these changes is directly related to the dose of ketamine and intervals between administration of compounds. Plasma levels of anesthetic are similar for all animals upon termination of hypnosis. © 1979 Birkhäuser Verlag.
引用
收藏
页码:1079 / 1081
页数:3
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